tag:blogger.com,1999:blog-77569893495630566162024-02-20T08:31:20.763-08:00John Moore Stellenbosch University Grape Cell Wall Research LaboratoryJohn Moore Plant Cell Wall Labhttp://www.blogger.com/profile/00259296029241988185noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-7756989349563056616.post-85866736825530801362016-01-31T03:41:00.000-08:002019-06-04T05:34:55.787-07:00HOMEPAGE<b><br /></b>
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<b><span lang="EN-US" style="color: maroon; font-size: 27pt;">Dr. John P. <st1:personname w:st="on">Moore</st1:personname><o:p></o:p></span></b></div>
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<i><span lang="EN-US" style="font-size: 14pt;">Senior Researcher
in Grapevine Biochemistry and Biotechnology<o:p></o:p></span></i></div>
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<span lang="EN-US" style="font-size: 14pt;">Institute for Wine
Biotechnology</span><span lang="EN-US" style="font-size: 14pt;"><br />
Department of Viticulture and Oenology<br />
Stellenbosch University, South Africa<o:p></o:p></span></div>
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<span style="color: blue; font-family: "arial" , sans-serif;"><b><a href="https://www.researchgate.net/profile/John_Moore18">https://www.researchgate.net/profile/John_Moore18</a></b></span></div>
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<span style="color: blue; font-family: "arial" , sans-serif;"><span style="line-height: 16px; white-space: nowrap;"><b><a href="https://www.blogger.com/goog_760236702"><br /></a></b></span></span></div>
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<span style="color: blue; font-family: "arial" , sans-serif;"><span style="line-height: 16px; white-space: nowrap;"><b><a href="https://za.linkedin.com/in/john-moore-62907625">https://za.linkedin.com/in/john-moore-62907625</a></b></span></span><br />
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<strong><span style="color: blue; font-family: "arial";"><a href="http://loop.frontiersin.org/people/32744/overview">http://loop.frontiersin.org/people/32744/overview</a></span></strong><br />
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<strong><span style="color: #3d85c6; font-family: "arial";"><a href="http://sun.academia.edu/JohnMooreStellenbosch">http://sun.academia.edu/JohnMooreStellenbosch</a></span></strong></div>
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<b><span style="font-family: "arial" , "helvetica" , sans-serif; font-size: large;">BACKGROUND</span></b><br />
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<b><span lang="EN-GB" style="color: #c00000; font-family: "arial" , "helvetica" , sans-serif; font-size: 10pt;">DOCTORAL RESEARCH AND POST-DOCTORAL
CAREER</span></b><span lang="EN-GB" style="color: #c00000; font-size: 10pt;"><o:p></o:p></span><br />
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<span lang="EN-GB" style="font-family: "arial" , "helvetica" , sans-serif; line-height: 150%;">I completed my studies at
the <st1:place w:st="on"><a href="http://www.uct.ac.za/"><span style="color: blue;">University of Cape Town</span></a></st1:place> where I
obtained undergraduate degrees in Biochemistry and a doctorate in Molecular and
Cell Biology. My PhD thesis entitled <i>The
role of polyphenols and the cell wall in relation to the desiccation tolerance
of the resurrection plant <u>Myrothamnus flabellifolia</u> (Welw.) </i>was
performed under the principal supervision of the late Associate Professor Wolf
Brandt. Through this research work, while under the co-supervision of Professor
Jill Farrant, I developed a keen interest in the desiccation and drought
tolerance mechanisms of plants. In addition, I became very interested in the
chemistry of plant polyphenols and the biochemistry of plant cell walls. During
my PhD I spent research periods at the <a href="http://www.univ-rouen.fr/"><span style="color: blue;">University of Rouen</span></a> in <st1:place w:st="on"><st1:country-region w:st="on">France</st1:country-region></st1:place> where I developed expertise
in the biochemistry and microscopy of plant cell walls under the supervision of
Professor Azeddine Driouich. After obtaining my doctorate I worked as a
post-doctoral fellow at the <a href="http://www.ed.ac.uk/"><span style="color: blue;">University of Edinburgh</span></a> in <st1:place w:st="on"><st1:country-region w:st="on">Scotland</st1:country-region></st1:place>. My research focused on
the mechanisms of phenolic coupling, using isotope-based metabolic methods,
within the walls of suspension cultured maize (<i>Zea mays</i>) cells in the laboratory of Professor Stephen Fry. Towards
the end of 2007 I joined the academic staff of the <a href="http://www.sun.ac.za/english/faculty/agri/wine-biotech"><span style="color: blue;">Institute for Wine Biotechnology</span></a> (IWBT) at <st1:place w:st="on"><a href="http://www.sun.ac.za/english"><span style="color: blue;">Stellenbosch University</span></a></st1:place> where I was
appointed as a researcher, and subsequently promoted to senior researcher. </span></div>
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<b><span lang="EN-GB" style="color: maroon; font-family: "arial" , "helvetica" , sans-serif; font-size: 10pt;">GRAPEVINE
AND WINE SCIENCES<o:p></o:p></span></b></div>
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<span lang="EN-GB" style="line-height: 150%;"><span style="font-family: "arial" , "helvetica" , sans-serif;">My research focus is on plant cell walls and plant polyphenols. I am interested in Grapevine Molecular Physiology and Biochemistry, Plant Glycobiology and Wine Chemistry. The overarching goals are to improve the scientific understanding around the areas of
disease resistance, fruit quality and abiotic stress (i.e. drought) tolerance
of <i>Vitis vinifera</i> (grapevine)
cultivars. Current research includes unravelling the <i>in vitro</i>, <i>in vivo</i> and <i>in planta</i> interactions between
endopolygalacturonases, polygalacturonase inhibitory proteins (PGIPs) and the
cell wall of <i>Vitis vinifera</i> in
response to fungal pathogen infection. Pathogens studied include <i>Botrytis cinerea</i>, a fungus responsible
for both grey and noble rot in grapevine. Areas of interest include grape berry
ripening and water deficit from the perspective of the plant cell wall. Current
research concerns the role of carbohydrate active enzymes in grape berry
deconstruction during winemaking. A further strand of research undertaken involves investigating the role of
mannoproteins in relation to growth and fermentation phenotypes of wine yeast (<i>Saccharomyces cerevisiae</i>). The approach
taken is multi-disciplinary in nature involving techniques from a range of
fields (i.e. molecular biology, chemistry, biochemistry (enzymology),
microscopy, immunocytochemistry and spectroscopy). Research funders include the
<a href="http://www.nrf.ac.za/">National Research Foundation</a> (South Africa), <a href="http://www.sun.ac.za/">Stellenbosch University</a>, <a href="http://www.winetech.co.za/">Winetech</a>
(Wine Industry Network of Expertise and Technology), SATI (South African Table
Grape Industry), contract research (e.g. BIO-Laffort, Bordeaux, France), The Royal Society (London, United Kingdom) and the South African
Government THRIP (Technology and Human Resources in Industry Programme).</span><span style="font-size: 10pt;"><o:p></o:p></span></span><br />
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<b>THE GREAT WALL OF CHINA</b></div>
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